Title of article
MYC gene amplification in double minute chromosomes in an aggressive large B-cell lymphoma with leukemic presentation: a case report
Author/Authors
Alseraye، نويسنده , , Kevin F. and Padmore، نويسنده , , R. and Wozniak، نويسنده , , M. and McGowan-Jordan، نويسنده , , J.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
3
From page
76
To page
78
Abstract
Double-minute chromosomes (dmin) are small chromatin particles that lack a centromere. They represent extrachromsomal form of gene amplification. Dmin are very rarely encountered in lymphoid neoplasms. We describe a case of a leukemic presentation of large B-cell lymphoma with dmin. Fluoresence in situ hybridization analysis identified these dmin as comprising MYC genes.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
2009
Journal title
Cancer Genetics and Cytogenetics
Record number
1829792
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