Author/Authors :
Bao، نويسنده , , Sumi and Guttmann، نويسنده , , Charles R.G and Mugler III، نويسنده , , John P and Brookeman، نويسنده , , James R and Panych، نويسنده , , Lawrence P and Kraft، نويسنده , , Robert A and Oshio، نويسنده , , Koichi and Jaramillo، نويسنده , , Diego and Jolesz، نويسنده , , Ferenc A and Williamson، نويسنده , , Daniel S and Mulkern، نويسنده , , Robert V، نويسنده ,
Abstract :
Lipid characterization of bone marrow in vivo with proton magnetic resonance spectroscopy was performed using Spin-Echo Planar Spectroscopic Imaging sequences. The methods are shown capable of rapidly generating two-dimensional chemical shift imaging data sets suitable for measuring lipid indices that reflect unsaturation levels among triglycerides, as demonstrated in oil phantoms and bone marrow from a healthy volunteer. The volume coverage, spatial resolution, acquisition speed, and spectral characteristics of Spin-Echo Planar Spectroscopic Imaging should make it attractive for clinical studies of diseases affecting normal lipid chemical composition.
