Title of article
Derivative (1;18)(q10;q10) in essential thrombocythemia
Author/Authors
Azuma، نويسنده , , Taichi and Yamanouchi، نويسنده , , Jun and Inoue، نويسنده , , Katsuji and Kohno، نويسنده , , Masashi and Narumi، نويسنده , , Hiroshi and Fujiwara، نويسنده , , Hiroshi and Yakushijin، نويسنده , , Yoshihiro and Hato، نويسنده , , Takaaki and Yasukawa، نويسنده , , Masaki، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
3
From page
62
To page
64
Abstract
This study reports the association of the chromosomal abnormality derivative (1;18)(q10;q10) with essential thrombocythemia (ET) occurring in a 75-year-old woman. Allele-specific polymerase chain reaction also revealed a V617F mutation in the Janus Kinase 2 gene (JAK2) in the platelet compartment in this patient. The der(1;18)(q10;q10) abnormality has previously been reported in two cases of myeloid disorders. The etiological implications for ET of this combination of chromosomal abnormality and JAK2 mutation still remain elusive. This is a novel report of derivative (1;18)(q10;q10) abnormality in ET.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
2010
Journal title
Cancer Genetics and Cytogenetics
Record number
1830491
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