• Title of article

    Essential thrombocythemia with myelofibrosis transformed into acute myeloid leukemia with der(1;15)(q10;q10): case report and literature review

  • Author/Authors

    Charafeddine، نويسنده , , Khalil M. and Mahfouz، نويسنده , , Rami A. and Zaatari، نويسنده , , Ghazi S. and Ibrahim، نويسنده , , Georges Y. and Muwakkit، نويسنده , , Samar A. and Najm، نويسنده , , Nada D. and Farra، نويسنده , , Chantal G. Lamontagne، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    6
  • From page
    28
  • To page
    33
  • Abstract
    Translocations involving chromosomes 1 and 15 are uncommon in hematologic malignancies. So far, only 42 cases have been reported with t(1;15) as a reciprocal or complex chromosomal abnormalities. We herein report the first case in the literature, to our knowledge, of a 44-year-old female with essential thrombocythemia and severe myelofibrosis who developed acute myeloid leukemia (AML-M4) with der(1;15)(q10;q10) after 13 years of treatment. In addition, we reviewed the literature for all up-to-date published cases with t(1;15).
  • Journal title
    Cancer Genetics and Cytogenetics
  • Serial Year
    2010
  • Journal title
    Cancer Genetics and Cytogenetics
  • Record number

    1830577