Author/Authors :
Oh، نويسنده , , Seung Hwan and Park، نويسنده , , Tae Sung and Cho، نويسنده , , Sun-Young and Kim، نويسنده , , Min Jin and Huh، نويسنده , , Jungwon and Kim، نويسنده , , Bomi and Song، نويسنده , , Sae Am and Lee، نويسنده , , Ja Young and Jun، نويسنده , , Kyung Ran and Shin، نويسنده , , Jeong Hwan and Kim، نويسنده , , Hye-Ran and Lee، نويسنده , , Jeong Nyeo، نويسنده ,
Abstract :
Translocation (10;17)(p13-15;q12-21) in acute leukemia is rarely reported in the literature. Here, we present both a novel t(10;17) case study and a review of relevant literature on t(10;17) in acute leukemia (10 cases). In summary, we came to the following preliminary conclusions: t(10;17) is associated with poorly differentiated acute leukemia subtype [90%; eight cases of acute myeloid leukemia (AML M0, M1) and one case of acute undifferentiated leukemia], phagocytic activity by blasts occurs (30%), and the survival time was short in three of the seven t(10;17) cases for whom follow-up data were available (median, 8 months). More clinical studies concerning the prognosis, treatment response, and survival of patients with t(10;17) are necessary.
