Title of article
Venodilatory effect of pranidipine, a calcium channel blocker, monitored with perfluorocarbon in vivo 19F-NMR spectroscopy
Author/Authors
Sogabe، نويسنده , , Takayuki and Mori، نويسنده , , Toyoki and Ohura، نويسنده , , Makoto and Tominaga، نويسنده , , Michiaki and Koga، نويسنده , , Keiko and Yabuuchi، نويسنده , , Youichi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
6
From page
1011
To page
1016
Abstract
We previously reported that the 19F-NMR signal intensity of perfluorocarbon was increased by a venodilator, nitroglycerine, and decreased by an arteriodilator, hydralazine. In the present study, we demonstrated that pranidipine, a calcium channel blocker, increased the intensity of the FC-43 signal, while nifedipine, a prototype of calcium channel blockers, did not. These results suggest that pranidipine dilates the venous system in contrast to nifedipine.
Keywords
19F-NMR , Pranidipine , perfluorocarbon , Rat gastrocnemius
Journal title
Magnetic Resonance Imaging
Serial Year
2000
Journal title
Magnetic Resonance Imaging
Record number
1830824
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