Reconstructing very short TE phase rotation spectral data collected with multichannel phased-array coils at 3 T

Phased-array volume coils were used in conjunction with the phase rotation STEAM (PR-STEAM) spectroscopy technique to acquire very short TE data from the anterior cingulate gyrus at 3 T. A method for combining PR-STEAM data from multiple subcoils is presented. The data were acquired from seven healthy participants using PR-STEAM (repetition time/mixing time/echo time=3500/10/6.5 ms, 6 cm3, NEX=128, spectral width=2000 Hz, 2048 complex points, Δφ1=135°, Δφ2=22.5°, Δφ3=112.5° and ΔφADC=0°). In addition to the primary metabolites, LCModel fit results suggest that glutathione and glutamate can also be identified with Cramér–Rao lower bounds of 10% or less.