Title of article
N-Acyl-2-benzoxazolinones in titanium-mediated aldol reactions
Author/Authors
Burlingame، نويسنده , , Mark A. and Mendoza، نويسنده , , Esteban and Ashley، نويسنده , , Gary W.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
2961
To page
2964
Abstract
N-Acyl-2-benzoxazolinones readily form trichlorotitanium enolates that react rapidly with aldehydes to provide crystalline syn-aldol adducts in high yield. The resulting products are simply converted to amides, esters, and thioesters. A simple, economical synthesis of 3-hydroxy-2-methylpentanoate N-propionylcysteamine thioesters based on these findings is presented.
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841219
Link To Document