Title of article
Highly diastereoselective aldol additions to five-ring N,O-acetals
Author/Authors
Brunner، نويسنده , , Martin and Koskinen، نويسنده , , Ari M.P. Koskinen، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
3063
To page
3065
Abstract
Highly diastereoselective aldol additions of pure (2R,4S)-2-tert-butyloxazolidinone-3,4-dicarboxylic acid 3-tert-butyl ester 4-methyl ester 1 are reported. While achiral carbonyl compounds lead to mixtures of diastereomers, the double stereodifferentiation of chiral aldehydes gave a single product isomer. The relative and absolute configurations of the aldol products were assigned by NOESY.
Keywords
natural products , asymmetric synthesis , Myriocin
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841254
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