Title of article
The facile solid-phase synthesis of cholesterol-based polyamine lipids
Author/Authors
Oliver، نويسنده , , Morag and Jorgensen، نويسنده , , Michael R. and Miller، نويسنده , , Andrew، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
3105
To page
3107
Abstract
A facile solid-phase methodology for the production of cholesterol-based polyamines useful in mediating nucleic acid delivery for gene therapy is described. The methodology is compatible with a range of polyamines producing a library of lipids in excellent yields (>87%) and purity.
Keywords
nonviral gene therapy , Cationic lipids , polyamines , solid-phase synthesis
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841273
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