Title of article
Asymmetric 1,3-dipolar cycloadditions of a chiral nonracemic glyoxylic azomethine imine
Author/Authors
Chung، نويسنده , , Florence and Chauveau، نويسنده , , Ariane and Seltki، نويسنده , , Mohamed and Bonin، نويسنده , , Martine and Micouin، نويسنده , , Laurent، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
3127
To page
3130
Abstract
The reactivity of a chiral nonracemic glyoxylic azomethine imine has been investigated. This species reacts with a wide range of dipolarophiles, with a complete regio- and facial stereoselectivity. The introduction of an electron-withdrawing substituent on the ylide leads to a lower endo selectivity with electron-withdrawing dipolarophiles, but to an improved exo selectivity with styrene derivatives when compared to the reactivity of aliphatic- or aromatic-substituted ylides.
Keywords
asymmetric synthesis , Cycloadditions , Azomethine imine
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841283
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