Title of article
Catalytic enantioselective Strecker reaction of ketoimines using catalytic amount of TMSCN and stoichiometric amount of HCN
Author/Authors
Kato، نويسنده , , Nobuki and Suzuki، نويسنده , , Masato and Kanai، نويسنده , , Motomu and Shibasaki، نويسنده , , Masakatsu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
3153
To page
3155
Abstract
Catalyst loading as low as 0.1 mol % was achieved in the enantioselective Strecker reaction of ketoimines. Excellent enantioselectivity was obtained with a combined use of a catalytic amount of TMSCN and a stoichiometric amount of HCN as a reagent, and a chiral gadolinium complex as a catalyst.
Keywords
Asymmetric catalysis , Ketoimines , Disubstituted amino acids , Strecker reaction , atom economy
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841293
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