Title of article
Peptide synthesis on fluorous support
Author/Authors
Mizuno، نويسنده , , Mamoru and Goto، نويسنده , , Kohtaro and Miura، نويسنده , , Tsuyoshi and Matsuura، نويسنده , , Takeshi and Inazu، نويسنده , , Toshiyuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
3425
To page
3428
Abstract
New fluorous supports were synthesized and used to prepare a peptide having a C-terminal COOH based on fluorous chemistry. The hexakisfluorous chain-type support was suitable for the synthesis of a pentapeptide or a peptide derivative on a fluorous support whose fluorine content is over 40 w/w%. A bioactive peptide, Leu-enkephalin, was easily synthesized using an Fmoc-strategy based on fluorous chemistry.
Keywords
Fluorous support , Leu-enkephalin , peptide synthesis , Fluorous Chemistry
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841403
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