Title of article
The diastereoselective synthesis of functionalised isoxazolidines using a Cope elimination/intramolecular nitrone cycloaddition strategy
Author/Authors
OʹNeil، نويسنده , , Ian A and Ramos، نويسنده , , V.Elena and Ellis، نويسنده , , Gemma L and Cleator، نويسنده , , Ed and Chorlton، نويسنده , , Alan P and Tapolczay، نويسنده , , David J and Kalindjian، نويسنده , , S.Barret، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
3659
To page
3661
Abstract
Functionalised hydroxylamine derivatives of (S)-prolinol prepared by a Cope elimination have been found to undergo oxidation to the nitrone either in the presence of air or a catalytic quantity of TPAP. These undergo intramolecular cycloaddition to give tricyclic isoxazolidines with high diastereoselectivity.
Keywords
Cope elimination , Nitrones , cycloaddition
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841489
Link To Document