Title of article :
Synthetic studies on thiostrepton family of peptide antibiotics: synthesis of the pentapeptide segment containing dihydroxyisoleucine, thiazoline and dehydroamino acid
Author/Authors :
Shuhei Higashibayashi، نويسنده , , Shuhei and Kohno، نويسنده , , Mitsunori and Goto، نويسنده , , Taiji and Suzuki، نويسنده , , Kengo and Mori، نويسنده , , Tomonori and Hashimoto، نويسنده , , Kimiko and Nakata، نويسنده , , Masaya، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
The dihydroxyisoleucine-, thiazoline- and dehydroamino acid-containing pentapeptide of the thiostrepton family of peptide antibiotics was synthesized, which featured the β-lactone opening by phenylselenylation, the vinylzinc addition to the chiral sulfinimine, the Wipf oxazoline–thiazoline conversion method and the oxidative syn-elimination of the phenylseleno group.
Keywords :
Thioamides , thiazolines , sulfinimines , Dihydroxyisoleucine , Thiostrepton
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
