Title of article
The remarkable role of water during the chemoselective reduction of ketones mediated by metallic aluminium
Author/Authors
Bhar، نويسنده , , Sanjay and Guha، نويسنده , , Sharmistha، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
3775
To page
3777
Abstract
Diaryl ketones are reduced selectively to the corresponding benzhydrols in good yield by aluminium powder in the presence of sodium hydroxide in the solvent system MeOH:H2O=2:1 whereas dialkyl ketones, α-tetralone, aryl alkyl ketones and cycloalkanones remain mostly unaffected. Interestingly, diaryl ketones remain totally unchanged by the present reagent combination in the absence of water, that is in anhydrous methanol.
Keywords
Reduction , Aluminium and compounds , solvents and solvent effects
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841538
Link To Document