Title of article :
Titanium(II)-mediated cyclization of (silyloxy)enynes: a synthesis of the C9–C19 subunit of dictyostatin-1
Author/Authors :
OʹNeil، نويسنده , , Gregory W. and Phillips، نويسنده , , Andrew J.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
Cyclization of (silyloxy)enynes with ClTi(i-PrO)3 and i-PrMgCl gives cyclic siloxanes. This cyclization offers a new approach to mixed polyacetate-polypropionate polyketides, and has been applied to the synthesis of the C9–C19 subunit of dictyostatin-1.
Keywords :
total synthesis , Dictyostatin , Enyne cyclization
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
