Title of article
Titanium(II)-mediated cyclization of (silyloxy)enynes: a synthesis of the C9–C19 subunit of dictyostatin-1
Author/Authors
OʹNeil، نويسنده , , Gregory W. and Phillips، نويسنده , , Andrew J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
4253
To page
4256
Abstract
Cyclization of (silyloxy)enynes with ClTi(i-PrO)3 and i-PrMgCl gives cyclic siloxanes. This cyclization offers a new approach to mixed polyacetate-polypropionate polyketides, and has been applied to the synthesis of the C9–C19 subunit of dictyostatin-1.
Keywords
total synthesis , Dictyostatin , Enyne cyclization
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841758
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