Title of article
Six-membered nitrogen ring formation by radical cyclization of trichloroacetamides with enones. A synthetic entry to cis-perhydroisoquinoline-3,6-diones
Author/Authors
Vila، نويسنده , , Xavier and Quirante، نويسنده , , Josefina and Paloma، نويسنده , , Laura and Bonjoch، نويسنده , , Josep، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
4661
To page
4664
Abstract
Intramolecular reactions between 1-(carbamoyl)dichloromethyl radicals and enones acting as radical acceptors are reported for the first time. The Bu3SnH promoted 6-exo reaction of trichloroacetamides with enones, avoiding the 1,5-hydrogen transfer, constitutes a new synthetic entry to cis-perhydoisoquinoline-3,6-diones.
Keywords
Nitrogen Heterocycles , radical cyclization , Trichloroacetamides , Isoquinolines , Madangamines
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842036
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