Title of article
Intramolecular cyclization reactions of aziridines with π-nucleophiles
Author/Authors
Bergmeier، نويسنده , , Stephen C. and Katz، نويسنده , , Steven J. and Huang، نويسنده , , Junfeng and McPherson، نويسنده , , Howard and Donoghue، نويسنده , , Patrick J. and Reed، نويسنده , , Damon D.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
5011
To page
5014
Abstract
We have found that aziridines will react with a variety of π-nucleophiles in intramolecular cyclization reactions to produce nitrogen containing core structures found in a variety of bioactive molecules. These cyclizations are more general and facile than corresponding intermolecular reactions. We have examined the effects of ring size, π-nucleophile identity and substitution on this reaction.
Keywords
Aziridines , Bicyclic heterocyclic compounds , Amines
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842198
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