Title of article :
First total synthesis of (+)-viroallosecurinine
Author/Authors :
Honda، نويسنده , , Toshio and Namiki، نويسنده , , Hidenori and Watanabe، نويسنده , , Masayuki and Mizutani، نويسنده , , Hirotake، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
The first diastereoselective chiral synthesis of (+)-viroallosecurinine, isolated from Securinega virosa as a cytotoxic alkaloid, was achieved by using a chelation-controlled addition of an alkyne moiety to the corresponding ketone, and a ring-closing metathesis, as key reactions.
Keywords :
Chelation-controlled addition , Securinega alkaloid , Diastereoselective total synthesis , (+)-Viroallosecurinine , Ring closing-metathesis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
