Author/Authors :
Zhang، نويسنده , , Mingbao and Reeves، نويسنده , , Raymond and Bi، نويسنده , , Cheng and Dally، نويسنده , , Robert and Ladouceur، نويسنده , , Gaetan and Bullock، نويسنده , , William and Chin، نويسنده , , Jefferson، نويسنده ,
Abstract :
Three novel, optically active, 6-substituted 2-(aminomethyl)chromans were synthesized from readily available chroman 2-carboxylic acid precursors. These chroman-containing primary amines are useful building blocks for the synthesis of chroman-derived pharmaceutical agents.
Keywords :
Friedel–Crafts alkylation , building blocks , chromans , Heck reaction
