Title of article
A convenient synthesis of 1,4-disubstituted imidazoles
Author/Authors
He، نويسنده , , Yong and Chen، نويسنده , , Yingzhong and Du، نويسنده , , Hongwang and Schmid، نويسنده , , Lesley A and Lovely، نويسنده , , Carl J، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
5529
To page
5532
Abstract
An efficient method for the regioselective protection of 4-alkyl-, 4-iodo, 4-vinylimidazoles has been developed via an alkylation–isomerization sequence with various imidazole-protecting groups. The initially formed mixture of 4/5-alkyl-, 4/5-iodo, and 4/5-vinylimidazoles are isomerized to the corresponding 4-isomers on treatment of a DMF solution with a small amount of RX and heating at 75 °C.
Keywords
imidazoles , regioselective , PROTECTION , Isomerization
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842483
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