Title of article :
A convenient and highly stereoselective synthesis of 14-substituted 8,13-diazaoestrone analogues by domino ring closures
Author/Authors :
Lلzلr، نويسنده , , Lلszlَ and Kivelن، نويسنده , , Henri and Pihlaja، نويسنده , , Kalevi and Fülِp، نويسنده , , Ferenc، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
By means of convenient domino ring closure reactions of 1-(2-aminoethyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 2 and γ-oxo-acids, 14-substituted 8,13-diazaoestrone derivatives (5 and 6) were formed with ∼100% diastereoselectivity.
Keywords :
diamines , Isoquinolines , Azasteroids , stereoselective synthesis , domino reactions
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
