Title of article
Novel trichothecanes, paecilomycine A, B, and C, isolated from entomopathogenic fungus, Paecilomyces tenuipes
Author/Authors
Kikuchi، نويسنده , , Haruhisa and Miyagawa، نويسنده , , Yasuhiro and Sahashi، نويسنده , , Yuko and Inatomi، نويسنده , , Satoshi and Haganuma، نويسنده , , Asami and Nakahata، نويسنده , , Norimichi and Oshima، نويسنده , , Yoshiteru، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
6225
To page
6228
Abstract
Paecilomycine A (1), B (2), and C (3) were isolated from cultivated fruiting bodies of Paecilomyces tenuipes (Isaria japonica), which is a popular entomopathogenic fungus used in folk medicine and health foods in China, Korea, and Japan. The structures of 1–3 were deduced from their spectroscopic data and their absolute configurations were elucidated by preparing their MPA esters. Compound 1 showed activity in the neurotrophic factor biosynthesis in glial cells.
Keywords
Paecilomyces tenuipes , Trichothecane , PC-12 cell , glial cell
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842921
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