Title of article
Efficient synthesis of extended guanine analogues designed for recognition of an A·T inverted base pair in triple helix based-strategy
Author/Authors
Van Craynest، نويسنده , , Nathalie and Guianvarc’h، نويسنده , , Dominique and Peyron، نويسنده , , Corinne and Benhida، نويسنده , , Rachid، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
6243
To page
6247
Abstract
We report herein an efficient synthesis of new nucleosides N1, N2, and N3 as extended guanine analogues, derived from aminobenzimidazole and thymine or 5-substituted uracil. These nucleosides were devised for the recognition of an A·T inverted base pair by three hydrogen bonds, in triple helix-based technology.
Keywords
Extended nucleosides , Triple helix , Molecular recognition
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842927
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