Title of article :
Boron trifluoride-induced reactions of phenylglycidyl ethers: a convenient synthesis of enantiopure, stereodefined fluorohydrins
Author/Authors :
Islas-Gonzلlez، نويسنده , , Gabriela and Puigjaner، نويسنده , , Cristina and Vidal-Ferran، نويسنده , , Anton and Moyano، نويسنده , , Albert and Riera، نويسنده , , Antoni and Pericàs، نويسنده , , Miquel A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
Ring-opening hydrofluorination of enantiomerically pure (2S,3S)-3-arylglycidyl ethers (aryl = phenyl, 4-trifluoromethylphenyl) by boron trifluoride–diethyl ether under mild conditions provides β-fluoro alcohols in good yield in a stereospecific manner with complete regiocontrol.
Keywords :
Fluorohydrins , Boron trifluoride–etherate , Epoxyethers , epoxides , ring-opening , Fluoroalcohols
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
