Title of article
Halogen–magnesium exchange of m- and p-iodo or bromo-arenes bearing ortho-directing groups through ate complexes
Author/Authors
Xu، نويسنده , , Jiayi and Jain، نويسنده , , Nareshkumar and Sui، نويسنده , , Zhihua، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
6399
To page
6402
Abstract
m- or p-Iodinated, or brominated ω-phenoxyalcohols and phenols as well as halogenated indoles were subjected to halogen–magnesium exchange reactions with isopropyl magnesium bromide (iPrMgBr) or isopropyl magnesium di-n-butyl lithium ate complexes (iPrMgnBu2Li) at −78 °C to room temperature. iPrMgnBu2Li proved superior to prevent ortho-metallation of these substituted arenes.
Keywords
Magnesium–halogen exchange , ortho-Directing groups , Phenoxy alcohols , Phenols , ate complexes
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842992
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