Title of article
Metal-assisted synthesis of enantiopure spirocyclic β-lactams from azetidine-2,3-diones
Author/Authors
Alcaide، نويسنده , , Benito and Almendros، نويسنده , , Pedro and Mart??nez-del Campo، نويسنده , , Teresa and Rodr??guez-Acebes، نويسنده , , Raquel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
6429
To page
6431
Abstract
A novel approach to enantiopure spirocyclic β-lactams has been developed by using different intramolecular metal-catalyzed cyclization reactions in monocyclic unsaturated alcohols. The access to cyclization precursors, 2-azetidinone-tethered homoallylic alcohols, (buta-1,3-dien-2-yl)methanols, and α-allenols was achieved by regio and stereoselective addition of stabilized organo-indium reagents to azetidine-2,3-diones in aqueous environment.
Keywords
?-Lactams , Metals , Oxacycles , spirocycles
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843013
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