Title of article
Investigation into the mechanism of lithiation of 2,3-dihydrooxepin
Author/Authors
Yan، نويسنده , , Zhiqing and Sebastian، نويسنده , , John F.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
6551
To page
6555
Abstract
The NMR characterization of the trienolate product of lithiation of 2,3-dihydrooxepin with 6-lithiodihydropyran in THF is reported. The NMR spectra also support a direct ring opening upon allylic lithiation via an E2-type mechanism rather than vinylic lithiation or stepwise allylic lithiation. We also found the structure of the trienolate product of this reaction to be the Z, Z configuration.
Keywords
Trienolate , 3-Dihydrooxepin , lithiation , 2
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843064
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