Title of article
Highly stereoselective addition of silylphosphines to chiral aldehydes
Author/Authors
Kolodiazhnyi، نويسنده , , Oleg I. and Guliaiko، نويسنده , , Irina V. and Kolodiazhna، نويسنده , , Anastasia O. and Kudryashov، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
6955
To page
6957
Abstract
The reaction between diphenyl(trimethylsilyl)phosphine and chiral aldehydes proceeds with high stereoselectivity to give diastereomerically pure tertiary α-trimethylsiloxyalkylphosphines. The diastereomeric purity of the addition products was 90–100%. The products were purified via the formation of borane–phosphine complexes. The reaction of bis(trimethylsilyl)phenylphosphine with acetonide (R)-glyceraldehyde provides tertiary bis(glyceryl)phosphines.
Keywords
Silylphosphines , stereoselectivity , Chiral aldehydes , Chiral ?-trimethylsiloxyalkylphosphines
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843230
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