Title of article :
Synthesis and biological evaluation of two novel 2′-substituted tiazofurin analogues
Author/Authors :
Popsavin، نويسنده , , Mirjana and Torovic، نويسنده , , Ljilja and Koji?، نويسنده , , Vesna and Bogdanovi?، نويسنده , , Gordana and Popsavin، نويسنده , , Velimir، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
Two novel tiazofurin analogues, 2-(2-benzamido-2-deoxy-β-d-ribofuranosyl)thiazole-4-carboxamide 4 and 2-(2-azido-2-deoxy-β-d-ribofuranosyl)thiazole-4-carboxamide 5, have been synthesized starting from d-glucose and evaluated for their in vitro cytotoxicity against several human leukaemia and solid tumour cell lines.
Keywords :
2 , 5-Anhydro sugars , De novo synthesis , In vitro cytotoxicity , Tiazofurin analogues , thiazoles
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
