Author/Authors :
Yoshikawa، نويسنده , , Naoki and Tan، نويسنده , , Lushi and Yasuda، نويسنده , , Nobuyoshi and Volante، نويسنده , , Ralph P. and Tillyer، نويسنده , , Richard D.، نويسنده ,
Abstract :
Enantioselective syntheses of bicyclo[3.1.0]hexane carboxylic acid derivatives are described. The syntheses were achieved by an intramolecular cyclopropanation as the key step, starting from enantiomerically pure starting materials that are commercially available.
Keywords :
Cyclopropanation , Claisen rearrangement , Fluorinated cyclopropane , mGluR agonist
