Author/Authors :
Koizumi، نويسنده , , Fumito and Takahashi، نويسنده , , Yuichi and Ishiguro، نويسنده , , Hiroki and Tanaka، نويسنده , , Rieko and Ohtaki، نويسنده , , Shizuo and Yoshida، نويسنده , , Mayumi and Nakanishi، نويسنده , , Satoshi and Ikeda، نويسنده , , Shun-ichi، نويسنده ,
Abstract :
EI-1941-1 (1a) and EI-1941-2 (2a) accompanied by EI-1941-3 (3) have been isolated from culture broth of Farrowia sp. E-1941 as the inhibitors of interleukin-1β converting enzyme. The structures of 1a, 2a, and 3 were elucidated by the analysis of NMR and MS data, and finally the absolute stereochemistries of 1a and 2a were confirmed by optical rotation data, or X-ray crystallographic analysis of p-bromobenzoate, 2b, respectively.
