Title of article
Solid-phase synthesis of 5-aminotetrazoles
Author/Authors
Yu، نويسنده , , Yongping and Ostresh، نويسنده , , John M. and Houghten، نويسنده , , Richard A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
7787
To page
7789
Abstract
A solid-phase synthesis of 5-aminotetrazoles is described. Resin-bound thioureas were displaced by sodium azide in the presence of HgCl2 and following nucleophilic cyclization produced the resin-bound products. The desired 5-aminotetrazoles were cleaved from the resin using 95% trifluoroacetic acid in dichloromethane in good yield and purity.
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843544
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