Title of article :
Mechanism of an unusual decarboxylative cyclization
Author/Authors :
Kende، نويسنده , , Andrew S. and Henry، نويسنده , , Olivier and Chen، نويسنده , , Zecheng Wang، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
The mechanism of an unusual decarboxylative cyclization from 5-methoxy-1-(2-carboxyphenyl)-1,4-dihydro-4-oxopyridine-2-carboxylic acid (diacid) to 3-methoxypyrido[1,2-a]indole-2,10-dione (ketone) has been investigated. 13C-labeling has demonstrated that the carbonyl carbon of the ketone arises exclusively from the anthranilic acid carboxyl of the diacid. A zwitterionic mechanism has been proposed.
Keywords :
Mechanism , Decarboxylative cyclization
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
