Author/Authors :
Samoshin، نويسنده , , Vyacheslav V. and Chertkov، نويسنده , , Vyacheslav A. and Gremyachinskiy، نويسنده , , Dmitriy E. and Dobretsova، نويسنده , , Elena K. and Shestakova، نويسنده , , Alla K. and Vatlina، نويسنده , , Lidia P.، نويسنده ,
Abstract :
Protonation of trans-2-aminocyclohexanols leads to dramatic conformational changes: due to an intramolecular hydrogen bond a conformer with equatorial position of ammonio- and hydroxy-groups becomes predominant. The trans-2-aminocyclohexanol moiety has been used for pH-induced conformational switching of a crown ether and a podand.
Keywords :
trans-2-Aminocyclohexanol , pH-switch , Conformations , Cyclohexano crown ether
