Author/Authors :
Kawasaki، نويسنده , , Tsuneomi and Ishikawa، نويسنده , , Keisuke and Sekibata، نويسنده , , Hiromitsu and Sato، نويسنده , , Itaru and Soai، نويسنده , , Kenso، نويسنده ,
Abstract :
5-Pyrimidyl alkanol with up to 96% ee was formed using chiral organic–inorganic hybrid silsesquioxane in the enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde, in conjunction with asymmetric autocatalysis.
Keywords :
Chiral hybrid silsesquioxane , Asymmetric induction , asymmetric synthesis , Asymmetric autocatalysis
