Title of article
A mild and selective method for N-dealkylation of tertiary amines
Author/Authors
Bhat، نويسنده , , Ramakrishna G. and Ghosh، نويسنده , , Yagnaseni and Chandrasekaran، نويسنده , , Srinivasan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
7983
To page
7985
Abstract
Alkyl groups can be cleaved efficiently and selectively from tertiary alkyl amines using propargyl chloroformate. The propargyloxycarbonyl (Poc) protected secondary amines thus obtained can be deblocked under neutral and mild conditions using benzyltriethylammonium tetrathiomolybdate. The generality and compatibility of the method have been studied with a wide range of functionalities.
Keywords
tetrathiomolybdate , N-Dealkylation , Propargyl chloroformate
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843619
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