Title of article
A simplified green chemistry approach to the Biginelli reaction using ‘Grindstone Chemistry’
Author/Authors
Bose، نويسنده , , Ajay K. and Pednekar، نويسنده , , Suhas and Ganguly، نويسنده , , Subhendu N. and Chakraborty، نويسنده , , Goutam and Manhas، نويسنده , , Maghar S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
8351
To page
8353
Abstract
Grindstone Chemistry––a greatly evolved version of Toda’s method of grinding solids together for solvent-free chemical reactions––has been described and its usefulness illustrated by the successful application of this technique to a simplified process for conducting the multi-component Biginelli reaction for the synthesis of physiologically active tetrahydropyrimidinones.
Keywords
Tetrahydropyrimidinone , Reaction by grinding , solvent-free reaction , p-TSA as an acid catalyst
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843783
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