Title of article
A stereoselective synthesis of the C(1)–C(16) fragment of the bryostatins
Author/Authors
Ball، نويسنده , , Matthew and Baron، نويسنده , , Anne and Bradshaw، نويسنده , , Benjamin and Omori، نويسنده , , Hiroki and MacCormick، نويسنده , , Somhairle and Thomas، نويسنده , , Eric J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
8737
To page
8740
Abstract
A synthesis of the C(1)–C(16) fragment of the brysostatins has been developed. Key steps are the stereoselective copper(I) catalysed addition of allylmagnesium bromide to an alkynyl ester, a condensation of a βγ-unsaturated aldehyde with a ketophosphonate, and the formation of the B-ring under mild conditions by stereoselective intramolecular conjugate addition.
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843937
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