Title of article :
Total synthesis of (+)-bongkrekic acid
Author/Authors :
Shindo، نويسنده , , Mitsuru and Sugioka، نويسنده , , Tomoyuki and Umaba، نويسنده , , Yuko and Shishido، نويسنده , , Kozo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
Total synthesis of bongkrekic acid, an important apoptosis inhibitor, has been accomplished. The strategy includes inexpensive starting materials, asymmetric alkylation, anionic allyl coupling and oxidative manipulations. This process would provide a sufficient amount of bongkrekic acid and its analogues.
Keywords :
total synthesis , apoptosis , Carboxylic acid , Oxidation , natural product
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
