Title of article
New hydrosoluble perylene and coronene derivatives
Author/Authors
Franceschin، نويسنده , , Marco and Alvino، نويسنده , , Antonello and Ortaggi، نويسنده , , Giancarlo and Bianco، نويسنده , , Armandodoriano، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
6
From page
9015
To page
9020
Abstract
Several lipophilic perylene and coronene derivatives, employed mainly as liquid crystalline dyes are known and their synthesis has been widely studied. We have applied an analogue strategy using hydrophilic substituents to obtain highly water soluble perylene diimides (4) and a new hydrosoluble coronene derivative (CORON, 6), whose molecular features appear particularly suitable for inducing G-quadruplex DNA structures and inhibiting human telomerase.
Keywords
Telomerase inhibitors , Perylene , Coronene , Hydrosoluble , G-Quadruplex
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1844048
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