Title of article :
The first stereoselective total synthesis of (6S)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one
Author/Authors :
Chandrasekhar، نويسنده , , S. and Narsihmulu، نويسنده , , Ch. and Sultana، نويسنده , , S. Shameem and Srinivasa Reddy، نويسنده , , M.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
Iterative asymmetric allylations and ring-closing metathesis have been effectively performed for the first stereoselective total synthesis of (6S)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one, a novel α,β-unsaturated-δ-lactone having antifungal activity, isolated from Ravensara crassifolia.
Keywords :
ring-closing metathesis , Maruoka asymmetric allylation , Keck asymmetric allylation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
