Title of article :
Trimethylsilyl cyanide addition to aldimines and its application in the synthesis of (S)-phenylglycine methyl ester
Author/Authors :
Prasad، نويسنده , , B.A. Bhanu and Bisai، نويسنده , , Alakesh and Singh، نويسنده , , Vinod K.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
The addition of TMSCN to a variety of arylaldimines (Strecker reaction) in the presence of LiClO4 or BF3·Et2O in acetonitrile has been studied. The reaction provided the addition products in very high yields. The method has been successfully utilized for the synthesis of (S)-phenylglycine methyl ester.
Keywords :
imines , TMSCN addition , ?-Amino acid
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
