Title of article
Solid-phase synthetic method for (±)-α-amino acids via phase-transfer catalytic alkylation
Author/Authors
Park، نويسنده , , Hyeung-geun and Kim، نويسنده , , Mi-Jeong and Park، نويسنده , , Mi-Kyung and Jung، نويسنده , , Hyun-Ju and Lee، نويسنده , , Jihye and Lee، نويسنده , , Yeon-Ju and Jeong، نويسنده , , Byeongseon and Lee، نويسنده , , Jeong-Hee and Yoo، نويسنده , , Mi-Sook and Ku، نويسنده , , Jin-Mo and Jew، نويسنده , , Sang-sup، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
93
To page
95
Abstract
A solid supported glycineimine t-butyl ester was designed and successfully applied to the synthesis of (±)-α-amino acids. The phase-transfer catalytic alkylation, followed by acidic hydrolysis and benzoylation gave N-benzoyl-α-amino acid tert-butyl esters in high yields (up to 92%).
Keywords
Phase-transfer catalytic alkylation , ?-Amino acid , solid-phase synthesis
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844350
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