Author/Authors :
Shubina، نويسنده , , Larisa K. and Fedorov، نويسنده , , Sergey N. and Radchenko، نويسنده , , Oleg S. and Balaneva، نويسنده , , Nadezhda N. and Kolesnikova، نويسنده , , Sophia A. and Dmitrenok، نويسنده , , Pavel S. and Bode، نويسنده , , Ann and Dong، نويسنده , , Zigang and Stonik، نويسنده , , Valentin A.، نويسنده ,
Abstract :
Two new diprenylquinones, glabruquinone A (desmethylubiquinone Q2) having cancer preventive properties and its minor isomer Glabruquinone B were isolated from the ascidian Aplidium glabrum. Their structures have been elucidated by NMR and mass spectra and confirmed by synthesis.
Keywords :
Polyprenylated quinones , Synthesis , Cancer preventive activity , marine natural products