Title of article
The first example of magnesium carbenoid 1,3-CH insertion reaction: a novel method for synthesis of cyclopropanes from 1-chloroalkyl phenyl sulfoxides in high yields
Author/Authors
Satoh، نويسنده , , Tsuyoshi and Musashi، نويسنده , , Jun and Kondo، نويسنده , , Atsushi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
599
To page
602
Abstract
Treatment of 1-chloroalkyl phenyl sulfoxides having a geminal methyl group or a geminal benzyl group at the 2-position in THF at −78 °C with isopropylmagnesium chloride gave magnesium carbenoids. Carbenoid 1,3-CH insertion reaction of the magnesium carbenoids took place instantaneously to afford cyclopropanes in high to quantitative yields.
Keywords
sulfoxide–magnesium exchange , Magnesium carbenoid , C–H insertion , Cyclopropane , Sulfoxide
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844548
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