Author/Authors :
Kang، نويسنده , , Yongfeng and Wang، نويسنده , , Rui and Liu، نويسنده , , Lei and Da، نويسنده , , Chao-shan and Yan، نويسنده , , Wen-jin and Xu، نويسنده , , Zhao-qing، نويسنده ,
Abstract :
New chiral oxazolidines were conveniently synthesized from natural amino acids in three simple steps with good yields. The use of chiral oxazolidine ligands for the enantioselective alkynylation of aldehydes provides a simple, practical and inexpensive method to generate chiral propargyl alcohols with 85–99% ee.
Keywords :
Aldehydes , Alkynes , Oxazolidines , Addition , Asymmetric catalysis
