Author/Authors :
Kawasaki، نويسنده , , Ikuo and Terano، نويسنده , , Masami and Yada، نويسنده , , Erika and Kawai، نويسنده , , Miwa and Yamashita، نويسنده , , Masayuki and Ohta، نويسنده , , Shunsaku، نويسنده ,
Abstract :
Reaction of 1-tert-butoxycarbonyl-3-cyclopentylidenemethyl-1H-indole with an excess of trifluoroacetic acid in dichloromethane at room temperature gave a cyclic dimer, 13-cyclopentyl-6,7,12,13-tetrahydrospiro[5H-cyclohepta[1,2-b:4,5-b′]diindole-6,1′-cyclopentane] in 73% yield as the sole product through a novel cyclo-dimerization process. Structure of the cyclic dimer derived from 5-bromo-1-t-butoxycarbonyl-3-cyclopentylidenemethyl-1H-indole was elucidated by X-ray crystallographic analysis.
