Author/Authors :
Liu، نويسنده , , Ji-Feng and Lee، نويسنده , , Jaekyoo and Dalton، نويسنده , , Audra M. and Bi، نويسنده , , Grace W. Yu، نويسنده , , Libing and Baldino، نويسنده , , Carmen M. and McElory، نويسنده , , Eric and Brown، نويسنده , , Matt، نويسنده ,
Abstract :
A practical synthesis of 2,3-disubstituted 3H-quinazolin-4-ones 1 with broad chemistry scope is described. The key step is the microwave promoted one-pot, two-step reaction sequence combining anthranilic acids, carboxylic acids, and amines providing efficient access to this important class of heterocycles.
